THR-317 in diabetic macular edema - under development by ThromboGenics
THR-317 is being evaluated in a Phase II trial in patients with diabetic macular edema (DME). In July 2017 the cooperation agreement from 2004 was renegotiated. Under the amended arrangement,ThromboGenics gains full and exclusive ownership of THR-317 for development and commercialization in all non-oncology indications. ThromboGenics will continue to carry all costs for the development of THR-317 in non-oncology indications, and BioInvent is entitled to five percent of the project’s economic value.
Patents for the antibody have been granted in Europe, the US, Japan and several additional countries, and patent applications are pending in further countries.